Immune receptor Totally Explained

Everything about Immune Receptor totally explained

An immune receptor (or immunologic receptor) is a receptor, usually on a cell membrane, which binds to a substance (for example, a cytokine) and causes a response in the immune system. One class of non-self molecules are called antigens (short for antibody generators) and are defined as substances that bind to specific immune receptors and elicit an immune response.

Types

The main receptors in the immune system are pattern recognition receptors (PRRs), Toll-like receptors (TLRs), killer activated and killer inhibitor receptors (KARs and KIRs), complement receptors, Fc receptors, B cell receptors and T cell receptors.

Receptor	Bind to	Function
pattern recognition receptors (PRRs)	pathogen-associated molecular patterns (PAMP)	inflammation --> destroying pathogen
Toll-like receptors (TLRs)		Mediate cytokine production --> inflammation and guiding immune cells to the site
killer activated and killer inhibitor receptors (KARs and KIRs)		Avails NK cells to identify abnormal host cells (KAR) or inhibit inappropriate host cell destruction (KIR)
complement receptors	complement proteins on for example microbes	Allow phagocytic and B cells to recognize microbes and immune complexes
Fc receptors	epitope-antibody complexes	Stimulate fagocytosis
B cell receptors	epitopes	B cell differentiation into plasma cells and proliferation
T cell receptors	epitopes bound to MHC	Activate T cells

Further Information

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